Small-sample estimation of negative binomial dispersion, with applications to SAGE data
نویسندگان
چکیده
منابع مشابه
Small-sample estimation of negative binomial dispersion, with applications to SAGE data.
We derive a quantile-adjusted conditional maximum likelihood estimator for the dispersion parameter of the negative binomial distribution and compare its performance, in terms of bias, to various other methods. Our estimation scheme outperforms all other methods in very small samples, typical of those from serial analysis of gene expression studies, the motivating data for this study. The impac...
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2007
ISSN: 1465-4644,1468-4357
DOI: 10.1093/biostatistics/kxm030